M30-M36 Systemic Connective Tissue Disorders

M30 Polyarteritis Nodosa & Related Conditions

Systemic connective tissue disorders M30-M36 >

 

Type 1 Excludes

autoimmune disease, single organ or single

cell-type -code to relevant condition category

Includes

autoimmune disease NOS

collagen (vascular) disease NOS

systemic autoimmune disease

systemic collagen (vascular) disease

 

Polyarteritis nodosa and related conditions M30- >

 

Type 1 Excludes

microscopic polyarteritis (M31.7)

 

Systemic lupus erythematosus (SLE) M32- >

 

Type 1 Excludes

lupus erythematosus (discoid) (NOS) (L93.0)

Clinical Information

A chronic, inflammatory, connective tissue disease

that can affect many organs including the joints,

skin, heart, lungs, kidneys, and nervous system.

It is marked by many different symptoms; however,

not everyone with sle has all of the symptoms.

A chronic, relapsing, inflammatory, and often

febrile multisystemic disorder of connective tissue,

characterized principally by involvement of the skin,

joints, kidneys, and serosal membranes. It is of

unknown etiology, but is thought to represent a

failure of the regulatory mechanisms of the autoimmune

system. The disease is marked by a wide range of system

dysfunctions, an elevated erythrocyte sedimentation rate,

and the formation of le cells in the blood or bone marrow.

 

Dermatopolymyositis M33- >

 

Clinical Information

A subacute or chronic inflammatory disease of muscle and skin,

marked by proximal muscle weakness and a characteristic skin

rash. The illness occurs with approximately equal frequency

in children and adults. The skin lesions usually take the form

of a purplish rash (or less often an exfoliative dermatitis)

involving the nose, cheeks, forehead, upper trunk, and arms.

The disease is associated with a complement mediated intramuscular

microangiopathy, leading to loss of capillaries, muscle ischemia,

muscle-fiber necrosis, and perifascicular atrophy. The childhood

form of this disease tends to evolve into a systemic vasculitis.

Dermatomyositis may occur in association with malignant neoplasms.

(from Adams et al., Principles of Neurology, 6th ed, pp1405-6)

An inflammatory muscle disease accompanied by muscle weakness

and skin rash

Progressive condition characterized by symmetric proximal muscular

weakness with elevated serum levels of muscle enzymes and a skin

rash, typically a purplish-red erythema on the face, and edema

of the eyelids and periorbital tissue; affected muscle tissue

shows degeneration of fibers with a chronic inflammatory reaction;

occurs in children and adults, and in the latter may be associated

with visceral cancer or other disorders of connective tissue.

Chronic, relapsing, inflammatory, and often febrile multisystemic

disorder of connective tissue, characterized principally by

involvement of the skin, joints, kidneys, and serosal membranes;

it is of unknown etiology, but is thought to represent a failure

of the regulatory mechanisms of the autoimmune system; the disease

is marked by a wide range of system dysfunctions, an elevated

erythrocyte sedimentation rate, and the formation of le cells

in the blood or bone marrow.

 

 

Systemic sclerosis [scleroderma] M34- >

 

Type 1 Excludes

circumscribed scleroderma (L94.0)

neonatal scleroderma (P83.8)

Clinical Information

A chronic disorder, possibly autoimmune, marked by excessive

production of collagen which results in hardening and

thickening of body tissues. The two types of systemic

scleroderma, limited cutaneous and diffuse cutaneous are

classified with focus on the extent of affected skin. A

relationship exists between the extent of skin area affected

and degree of internal organ/system involvement. Systemic

scleroderma can manifest itself in pulmonary fibrosis,

Raynaud's syndrome, digestive system telangiectasias,

renal hypertension and/or pulmonary hypertension.

 

 

A chronic multi-system disorder of connective tissue.

It is characterized by sclerosis in the skin, the lungs,

the heart, the gastrointestinal tract, the kidneys,

and the musculoskeletal system. Other important features

include diseased small blood vessels and autoantibodies.

The disorder is named for its most prominent feature

(hard skin), and classified into subsets by the extent

of skin thickening: limited scleroderma and diffuse scleroderma.

A disease that is marked by hardening and thickening of skin,

connective tissue that surrounds other tissues and organs,

and blood vessels.

A rare, chronic disease characterized by excessive deposits of

collagen in the skin or other organs

Systemic disorder of the connective tissue; manifested by

hardening and thickening of the skin, by abnormalities

involving the microvasculature and larger vessels, and by

fibrotic degenerative changes in various body organs including

the heart, lungs, kidneys, and gastrointestinal tract.

 

Other systemic involvement of connective tissue M35- >

 

Type 1 Excludes

reactive perforating collagenosis (L87.1)

 

 

Systemic disorders of connective tissue in diseases

classified elsewhere M36- >

 

Type 2 Excludes

arthropathies in diseases classified elsewhere (M14.-)

 

M31 Other Necrotizing Vasculopathies

M33 Dermatopolymyositis

M34 Systemic Sclerosis [Scleroderma]

M35 Other Systemic Involvement of Connective Tissue