Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and to treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants...Wikipedia

 

 

Manufacturer's Website: Rapamune                                                                                                                       Average retail cost: $900/month

Everolimus is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an inhibitor of mammalian target of rapamycin (mTOR). It is currently used as an immunosuppressant to prevent rejection of organ transplants and in the treatment of renal cell cancer and other tumours...Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                              Average retail cost: $1,000/month

Temsirolimus (codenamed CCI-779) is an intravenous drug for the treatment of renal cell carcinoma (RCC), developed by Wyeth Pharmaceuticals and approved by the U.S. Food and Drug Administration (FDA) in late May 2007...Wikipedia

 

 

Manufacturer's Website: Torisel                                                                                                                                   Average retail cost: $1,850/vial

Advanced Breast Cancer

 

AFINITOR® (everolimus) Tablets is a prescription medicine used to treat advanced hormone receptor-positive, HER2-negative breast cancer (advanced HR+ BC), along with the medicine exemestane, in postmenopausal women who have already received certain other medicines for their cancer.

 

Advanced Kidney Cancer

 

AFINITOR is a prescription medicine used to treat adults with advanced kidney cancer (renal cell carcinoma or RCC) when certain other medicines have not worked.

 

Advanced Pancreatic Neuroendocrine Tumor

 

AFINITOR is a prescription medicine used to treat adults with a type of pancreatic cancer known as pancreatic neuroendocrine tumor (PNET) that has progressed and cannot be treated with surgery.

 

AFINITOR is not for use in people with carcinoid tumors that actively produce hormones.

 

Progressive GI and Lung Neuroendocrine Tumor

 

AFINITOR is a prescription medicine used to treat adults with a type of cancer known as neuroendocrine tumor (NET) of the stomach and intestine (gastrointestinal) or lung that has progressed and cannot be treated with surgery.

 

AFINITOR is not for use in people with carcinoid tumors that actively produce hormones.

 

Renal Angiomyolipoma With Tuberous Sclerosis Complex

 

AFINITOR is a prescription medicine used to treat adults with a kidney tumor called angiomyolipoma, seen with a genetic condition called tuberous sclerosis complex (TSC), when their kidney tumor does not require surgery right away.

 

SEGA With Tuberous Sclerosis Complex

 

AFINITOR and AFINITOR DISPERZ™ (everolimus tablets for oral suspension) are prescription medicines used to treat adults and children with a genetic condition called tuberous sclerosis complex (TSC) who have a brain tumor called subependymal giant cell astrocytoma (SEGA) when the tumor cannot be removed completely by surgery.

 

 

 

Manufacturer's Website: Afinitor                                                                                                               Average retail cost: $14,000/month