Neoplasms C00-D49 >
Note
Functional activity
All neoplasms are classified in this chapter, whether they are functionally active or
not. An additional code from Chapter 4 may be used, to identify functional activity
associated with any neoplasm.
Morphology [Histology]
Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings
for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used
to identify the correct topography code. In a few cases, such as for malignant melanoma
and certain neuroendocrine tumors, the morphology (histologic type) is included in the
category and codes.
Primary malignant neoplasms overlapping site boundaries
A primary malignant neoplasm that overlaps two or more contiguous (next to each other)
sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the
combination is specifically indexed elsewhere. For multiple neoplasms of the same site
that are not contiguous, such as tumors in different quadrants of the same breast, codes
for each site should be assigned.
Malignant neoplasm of ectopic tissue
Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g.,
ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
Malignant neoplasm of lip C00- >
Use Additional
code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Type 1 Excludes
malignant melanoma of lip (C43.0)
Merkel cell carcinoma of lip (C4A.0)
other and unspecified malignant neoplasm of skin of lip (C44.0-)
Clinical Information
A primary or metastatic malignant neoplasm involving the lip.
Malignant neoplasm of base of tongue C01- >
Applicable To
Malignant neoplasm of dorsal surface of base of tongue
Malignant neoplasm of fixed part of tongue NOS
Malignant neoplasm of posterior third of tongue
Use Additional
code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Malignant neoplasm of other and unspecified parts of tongue C02- >
Use Additional
code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Malignant neoplasm of gum C03- >
Use Additional
code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Type 2 Excludes
malignant odontogenic neoplasms (C41.0-C41.1)
Includes
malignant neoplasm of alveolar (ridge) mucosa
malignant neoplasm of gingiva
Malignant neoplasm of floor of mouth C04- >
Use Additional
code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Malignant neoplasm of palate C05- >
Use Additional
code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Type 1 Excludes
Kaposi's sarcoma of palate (C46.2)
Malignant neoplasm of other and unspecified parts of mouth C06- >
Use Additional
code to identify:
alcohol abuse and dependence (F10.-)
history of tobacco use (Z87.891)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Malignant neoplasm of parotid gland C07- >
Use Additional
code to identify:
alcohol abuse and dependence (F10.-)
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Clinical Information
Cancer that forms in a parotid gland, the largest of the salivary glands, which make
saliva and release it into the mouth. There are 2 parotid glands, one in front of
and just below each ear. Most salivary gland tumors begin in parotid glands.
Malignant neoplasm of other and unspecified major salivary glands C08- >
Use Additional
code to identify:
alcohol abuse and dependence (F10.-)
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Type 1 Excludes
malignant neoplasms of specified minor salivary glands which are classified according
to their anatomical location
Type 2 Excludes
malignant neoplasms of minor salivary glands NOS (C06.9)
malignant neoplasm of parotid gland (C07)
Includes
malignant neoplasm of salivary ducts
Malignant neoplasm of tonsil C09- >
Use Additional
code to identify:
alcohol abuse and dependence (F10.-)
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Type 2 Excludes
malignant neoplasm of lingual tonsil (C02.4)
malignant neoplasm of pharyngeal tonsil (C11.1)
Clinical Information
Malignant neoplasm of the tonsils.
Malignant neoplasm of oropharynx C10- >
Use Additional
code to identify:
alcohol abuse and dependence (F10.-)
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Type 2 Excludes
malignant neoplasm of tonsil (C09.-)
Clinical Information
Malignant neoplasms of the oral cavity and pharynx
Malignant neoplasm of nasopharynx C11- >
Use Additional
code to identify:
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Clinical Information
A primary or metastatic malignant neoplasm involving the nasopharynx.
Malignant neoplasm of pyriform sinus C12- >
Applicable To
Malignant neoplasm of pyriform fossa
Use Additional
code to identify:
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Malignant neoplasm of hypopharynx C13- >
Use Additional
code to identify:
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Type 2 Excludes
malignant neoplasm of pyriform sinus (C12)
Clinical Information
A malignant neoplasm arising in the hypopharynx.
Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx C14- >
Use Additional
code to identify:
alcohol abuse and dependence (F10.-)
exposure to environmental tobacco smoke (Z77.22)
exposure to tobacco smoke in the perinatal period (P96.81)
history of tobacco use (Z87.891)
occupational exposure to environmental tobacco smoke (Z57.31)
tobacco dependence (F17.-)
tobacco use (Z72.0)
Type 1 Excludes
malignant neoplasm of oral cavity NOS (C06.9)
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