B20 Human immunodeficiency virus [HIV] disease

Human immunodeficiency virus [HIV] disease B20- >

 

Includes

acquired immune deficiency syndrome [AIDS]

AIDS-related complex [ARC]

HIV infection, symptomatic

Clinical Information

A disease caused by human immunodeficiency virus

(hiv). People with acquired immunodeficiency syndrome

are at an increased risk for developing certain cancers

and for infections that usually occur only in individuals

with a weak immune system.

A prodromal phase of infection with the human

immunodeficiency virus (hiv). Laboratory criteria separating

aids-related complex (arc) from aids include elevated or

hyperactive b-cell humoral immune responses, compared to

depressed or normal antibody reactivity in aids; follicular

or mixed hyperplasia in arc lymph nodes, leading to lymphocyte

degeneration and depletion more typical of aids; evolving

succession of histopathological lesions such as localization

of kaposi's sarcoma, signaling the transition to the

full-blown aids.

A syndrome resulting from the acquired deficiency of cellular

immunity caused by the human immunodeficiency virus (hiv). It

is characterized by the reduction of the helper t-lymphocytes

in the peripheral blood and the lymph nodes. Symptoms include

generalized lymphadenopathy, fever, weight loss, and chronic

diarrhea. Patients with aids are especially susceptible to

opportunistic infections (usually pneumocystis carinii pneumonia,

 cytomegalovirus (cmv) infections, tuberculosis, candida infections,

 and cryptococcosis), and the development of malignant neoplasms

 (usually non-hodgkin's lymphoma and kaposi's sarcoma). The human

 immunodeficiency virus is transmitted through sexual contact,

 sharing of contaminated needles, or transfusion of contaminated blood.

An acquired defect of cellular immunity associated with infection

by the human immunodeficiency virus (hiv), a cd4-positive t-lymphocyte

count under 200 cells/microliter or less than 14% of total lymphocytes,

and increased susceptibility to opportunistic infections and malignant

neoplasms. Clinical manifestations also include emaciation (wasting)

and dementia. These elements reflect criteria for aids as defined

by the cdc in 1993.

An infection caused by the human immunodeficiency virus.

Any state of infection accompanied by evidence of hiv in the body

(positive test for hiv genome, cdna, proteins, antigens, or antibodies);

 may be medically asymptomatic or symptomatic; use aids when appropriate.

Includes the spectrum of human immunodeficiency virus infections that

 range from asymptomatic seropositivity, thru aids-related complex

 (arc), to acquired immunodeficiency syndrome (aids).

One or more indicator diseases, depending on laboratory evidence of

hiv infection (cdc); late phase of hiv infection characterized by

marked suppression of immune function resulting in opportunistic

infections, neoplasms, and other systemic symptoms (niaid).