Aldurazyme® (laronidase) is indicated for patients with Hurler and Hurler-Scheie forms of Mucopolysaccharidosis I (MPS I) and for patients with the Scheie form who have moderate to severe symptoms.Aldurazyme is the name of the commercialized variant of the enzyme Iduronidase, which hydrolyzes the alpha-L-iduronic acid residues of dermatan sulfate and heparin sulfate. Produced in Chinese hamster ovaries by recombinant DNA technology, Aldurazyme is the manufactured by BioMarin Pharmaceutical Inc. and distributed by Genzyme Corporation (a subsidiary of Sanofi). Aldurazyme is administered as a slow intravenous infusion. The recombinant enzyme is 628 amino acids in length with 6 N-linked oligosaccharide modification sites and two oligosaccharide chains terminating in mannose sugars...Wikipedia

 

 

Manufacturer's Website: Aldurazyme                                                                                                      Average retail cost: $864/ 5ml vial

 

Search Terms: Aldurazyme, laronidase, Hurler, Hurler-Scheie, Mucopolysaccharidosis I (MPS I)